LOX and hepatocellular carcinoma: It has been reported that LOX is associated with several types of cancer, including breast, colorectal, prostate, gastric, and pancreatic cancer, head and neck squamous cell carcinoma, renal clear cell carcinoma, melanoma, oral and oropharyngeal squamous cell carcinoma, as well as basal and squamous cell skin carcinoma [7], with some more recent studies showing an association between LOX and HCC.