Obese PCOS participants had significantly higher leptin (24.5 ± 6.2 vs. 14.2 ± 5.8 ng/mL, p<0.001), resistin (11.6 ± 3.2 vs. 8.5 ± 2.9 ng/mL, p=0.013), TNF-α (5.8 ± 1.3 vs. 4.6 ± 1.1 pg/mL, p=0.038), IL-6 (6.2 ± 1.9 vs. 4.2 ± 1.5 pg/mL, p=0.041), and lower adiponectin (5.2 ± 1.4 vs. 7.8 ± 1.9 μg/mL, p=0.002). This evidence concerns the gene RETN and polycystic ovary syndrome.