After evaluating the expression patterns of the candidate genes in 31 tumor types using the GEPIA database (Supplementary Figure S1), we found that MSLN is expressed much higher in OV than in other types of tumors and MSLN expression was negligible in most normal tissues, with the exception of low-level expression observed in normal tissues corresponding to lung adenocarcinoma (LUAD, 65.68 TPM) and lung squamous cell carcinoma (LUSC, 64.68 TPM). This evidence concerns the gene MSLN and lung adenocarcinoma.