ACHE and early-onset autosomal dominant Alzheimer disease: Nevertheless, leaf extracts of our three varieties studied, as well as those of D. lotus cited above, present a less good affinity than our positive control, galantamine, which is a highly potent AchE inhibitor (IC50 is 0.23 μg/mL), which explains its use as a drug in Alzheimer's disease‐related cognitive disorders.