Our data show that higher AMH levels and lower SHBG, DHEAS, and APN levels, along with higher insulin levels and HOMA-IR scores, in cord blood of pregnancies with T2D, suggests that this type of pregestational diabetes may be associated with changes in hormones that regulate ovarian development and metabolic profile in the intrauterine environment of the offspring. The gene discussed is INS; the disease is type 2 diabetes mellitus.