However, the CD4+/CD8+ cell ratio was maintained in all tumor specimens (Figure 2F) with the percentage of CD4+ cells maintained in 5/8 tumors (P > 0.05, Figure 2D and S3E) and the percentage of CD8+ cells maintained in 7/8 tumors (P > 0.05, Figure 2E and S3F). Here, CD4 is linked to neoplasm.