Following 1e5 PFU infection, at 3 dpi in the liver, PEP-R619W M-cNK cells (CD11b+ CD49b+ CD49a− NK1.1+) have higher expression of (i) IFNγ, (ii) T-bet, (iii) granzyme B, and (iv) perforin, compared to PEP-WT M-cNK cells (Fig. 4A, i–iv). This evidence concerns the gene PRF1 and infection.