Similar results were seen in splenic CD8α− cDCs, which are likely type 2 conventional dendritic cells (cDC2s) (Fig. S3I–K), though there was a decrease in CD86 expression in PEP-null and PEP-R619W splenic CD8α− cDCs compared to PEP-WT post-infection (Fig. S3K) (48). The gene discussed is CD86; the disease is infection.