LCN2, an innate immune protein, has been identified as playing a pivotal role in iron regulation under both physiological and inflammatory conditions.[40] Recent studies show that LCN2 induces ferroptosis in multiple diseases, such as age‐related macular degeneration and lung cancer cachexia.[41, 42] Therefore, we chose LCN2 for further research. The gene discussed is LCN2; the disease is lung cancer.