SYNGAP1 and epilepsy: 2022). SYNGAP1 encodes a postsynaptic protein that regulates neuronal plasticity and synaptic connections. Haploinsufficiency of SYNGAP1 is associated with epilepsy, intellectual disability, and ASD‐like traits (Xing et al. 2016). Its role in glutamatergic signaling and synaptic plasticity suggests a potential link to BD, where disrupted NMDA receptor‐mediated signaling may underlie cognitive and mood dysregulation (Birtele et al. 2022; Kalkman 2012). These findings highlight the important role of SYNGAP1 in the shared neurodevelopmental mechanisms underlying diseases such as ASD and BD.