To investigate the biological role of EP300-AS1 in NSCLC cells, LUAD A549 and LUSC EBC1 cells were infected with recombinant lentiviruses carrying control shRNA (shCtrl) or two independent shRNAs targeting EP300-AS1 (shLnc-1 or shLnc-2). Here, EP300 is linked to non-small cell lung carcinoma.