Additionally, SH3BP5-AS1 promoted glycolysis via miR-6838-5p sponging and PTPN4 activation which is a non-receptor tyrosine phosphatase known to interact with autophagy regulators, and its upregulation contributes to autophagy activation, which in turn supports tumor cell survival and resistance under metabolic stress. This evidence concerns the gene SH3BP5 and neoplasm.