MCM7 and Hepatic fibrosis: H&E staining, Masson’s trichrome staining, immunohistochemistry, hydroxyproline content, the area of egg granuloma, qRT-PCR, and Western blot analysis of hepatic fibrosis markers collectively revealed that hepatocyte MCM7 overexpression significantly aggravated hepatic fibrosis in S. japonicum-infected mice (Fig. S4B–F).