This is in accordance with our previous report in a cohort of 36 patients with somatotroph adenomas naïve to medical therapy at surgery, that the number of tumor‐infiltrating CD68+ macrophages correlated with maximum adenoma diameter and was more numerous in somatotropinomas with Ki‐67 >3%.12 The gene discussed is MKI67; the disease is growth hormone secreting pituitary adenoma 1.