Low PIWIL2 expression in colon tumors was also correlated with poor patient survival among all tumor stages, when stratified by stages 1-3 combined, and even more pronounced in stage 4, using the Kaplan–Meier Plotter web-based tool (Fig. 2K-M), which is in agreement with the CNA data (Fig. 1D). This evidence concerns the gene PIWIL2 and colonic neoplasm.