To investigate the in vivo role of Cxcr1 in DCs during ALI pathogenesis, mice with a conditional DC‐specific Cxcr1 deletion (Cxcr1fl/flItgaxcre, referred to as Cxcr1i△DC/i△DC) and WT littermate controls (Cxcr1i△DC/+) were generated (Figure1A,B). Here, CXCR1 is linked to acute respiratory distress syndrome.