Network pharmacology and molecular docking analyses showed that key bioactive compounds, such as luteolin, dolichandrone B, salvionoside B, uncaric acid, oleanolic acid, and ursolic acid, effectively bind to proteins linked to chronic bronchitis (such as TNF, MMP-9, and PTGS2) through pathways like TNF and IL-17 signaling pathways. The gene discussed is IL17A; the disease is chronic bronchitis.