In conclusion, this study clarifies the correlation between lipids and cardiovascular disease, although the predictive value of a single APOB/APOA1 indicator for CAVD is relatively limited, but still statistically significant; it correlates better with CAVD than traditional lipid parameters, and the APOB/APOA1 ratio together with age, history of diabetes mellitus, DBP, Cys-c, and NLR constitutes a good predictive efficacy for CAVD in a combined model. Here, APOA1 is linked to cardiovascular disorder.