In addition, certain meningiomas harbor mutations in genes such as KDM5C, KDM6A, SMARCB1, and SMARCE1, which encode proteins involved in transcriptional chromatin remodeling (SMARCB1, SMARCE1) or histone demethylation (KDM5C, KDM6A). This evidence concerns the gene SMARCB1 and meningioma.