IGFBP3 and neoplasm: The qRT-PCR results revealed pronounced upregulation of TFF1, ITPKA, UBE2C, and IGFBP3, along with marked downregulation of SLC34A2 and SELENBP1 in tumor samples relative to adjacent normal tissues (Figures 9A–F), which was in strong agreement with the transcriptomic profiling outcomes.