In the multivariate analysis, after adjusting for UBE2C, AGGF1, microvessel density (MVD), tumor size, LNM, and TNM stage, positive VM status remained an independent predictor of mortality, increasing the risk by 2.1-fold (multivariate HR 2.107, 95% CI: 1.226–3.622, p=0.007). Here, AGGF1 is linked to neoplasm.