Multivariate models were developed to predict chemotherapy safety.<h4>Results</h4>Among the 16 variants analyzed in 82 patients, key findings included: The G allele of <i>GSTP1</i> (rs1695) was protective against neuropathy (OR = 0.147; p = 0.012) but increased mucositis risk (OR = 2.27; p = 0.036). Here, GSTP1 is linked to mucositis.