Higher maternal levels of IL-6, TNF-α, α1-antitrypsin, CRP, sVCAM, uric acid, and TBARS; lower sL-selectin in PE. In newborns of PE mothers: higher uric acid, α1-antitrypsin, CRP; lower leukocyte count, sL-selectin, lactoferrin, elastase/α1-antitrypsin ratio. Suggests an enhanced maternal and fetal inflammatory state linked to endothelial dysfunction and cytokine synthesis. The gene discussed is LTF; the disease is endothelial dysfunction.