Prophylactic antibiotics to reduce the incidence of grade ≥3 infectionsConsider antiviral and antifungal prophylaxis for high-risk patientsAdminister intravenous immunoglobulin (IVIG) for patients with recurrent infections and hypogammaglobulinemiaUse G-CSF for neutropenia prevention in patients receiving myelosuppressive therapyEnsure influenza, pneumococcal, and COVID-19 vaccines to prevent viral and bacterial infections. This evidence concerns the gene CSF3 and influenza.