The wild-type p53 in KKK-D068 (Vaeteewoottacharn et al., 2019) and an inactive mutant form of p53 in KKU-213A (or formerly known as M213) (Phimsen et al., 2012) suggest that the interplay between cGAS, STING, and p53 in MN-induced activation may differ among CCA cell lines and warrants further investigation. This evidence concerns the gene STING1 and cholangiocarcinoma.