The injected Gd-EOB-DTPA can be taken up by normal hepatocytes through the organic anion transporting polypeptide 1B3 (OATP1B3), which can show higher signals on the images (10); whereas, the surviving and new tumor tissues lack the expression of the related transport peptide 1B3, have poorer ability to uptake Gd-EOB-DTPA, then show lower signals in the hepatobiliary phase, forming a contrast with the surrounding normal tissue (10, 13, 18, 19). The gene discussed is SLCO1B3; the disease is neoplasm.