Early-Phase Clinical TrialsA small RCT showed that oral GGA increased HSP expression in human atrial tissue of CABG patients (van Marion et al., 2020). A Phase II trial (referred to as GENIALITY in the text) is ongoing to assess GGA for preventing postoperative AF (PoAF) (S Ramos et al., 2025). Here, HSP90B2P is linked to atrial fibrillation.