NPPB and familial dilated cardiomyopathy: However, no significant difference was observed between the two groups in the reduction of LVEDD (WMD: 0.09; 95% CI: 0.23–0.06; P = 0.207) and BNP levels (WMD: −326.66; 95% CI: −749.4 to 95.92; P = 0.128) for patients with DCM (Xia et al., 2020).