Tumor cells undergoing ICD express tumor-associated antigens and damage-associated molecular patterns (DAMPs), such as surface exposure of calreticulin (CRT) (“eat me” signal), release of high-mobility group box 1 (HMGB1) (“danger” signal), and secretion of adenosine triphosphate (ATP) (“find me” signal). The gene discussed is HMGB1; the disease is neoplasm.