Specifically, miR‐146a‐5p has been reported to bind directly to WNT2 [37], EGFR [38], NOTCH2 [39], TRAF6 [40], IRAK1 [41] and EIF5A2 [42] to inhibit EMT and act as a tumour suppressor in various human cancers. This evidence concerns the gene IRAK1 and cancer.