Given that the MZB-1 antibody reveals the MZB-1 protein, associated with the processing and secretion of immunoglobulins and present in the endoplasmic reticulum of B-cells in the marginal zone of lymphoid follicles, plasmablasts, and plasma cells,20 the authors decided to compare the mean expression area fraction of CD20 (B-cell marker) with the mean expression area fraction of MZB-1 in each leprosy group. Here, MZB1 is linked to leprosy.