Functionally, NGF upregulation and pro-oncogenic pathway activation are conducive to rescuing glioma and NB cells from pro-apoptotic factors, such as tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and kinase inhibitors, e.g., imatinib, dasatinib, crizotinib, cabozantinib, and axitinib (Lebedev et al. 2021, 2022; Benedetto et al. 2019). The gene discussed is NGF; the disease is neuroblastoma.