The expression of LDHA and SLC16A1 in all grade tumor samples (grades I to IV) in the GSE15824 dataset was not significantly different from that in the control group (P > 0.05, Fig. 1C and D), and the expression of LDHA in grade I to grade IV in the GSE16011 dataset was significantly lower than that in the control group (all P < 0.05, Fig. 1E). Here, LDHA is linked to neoplasm.