Among the serum studies, one compared serum lactate dehydrogenase (an important enzyme of the anaerobic metabolic pathway), C‐reactive protein (CRP), neutrophil‐to‐lymphocyte ratio (NLR), and platelet‐to‐lymphocyte ratio (PLR) in patients with IIH and healthy controls, finding that they were significantly higher in affected patients.28 This evidence concerns the gene CRP and pseudotumor cerebri.