MELTF and colorectal carcinoma: Using in silico tools along with in vitro and cell-based assays, we demonstrate that the CRC-dysregulated LINC01589, MELTF-AS1, and UXT-AS1 lncRNAs (i) are expressed in CRC, and other cancers as well, suggesting their probable role in diverse cancers; (ii) form stable G4s in vitro; (iii) harbor G4s that are detectable in CRC cells, notably for LINC01589 and UXT-AS1; (iv) harbor G4s that can be efficiently targeted by the prototype molecule PhpC in CRC cells, notably for UXT-AS1.