ADIPOQ and Fabry disease: In contrast, expression of GnasR201C in mature osteoblasts (Col1a1-Cre [72]) or Adipoq-lineage marrow progenitors (Adipoq-Cre [23]) either failed to induce FD lesions or induced tail-restricted lesions respectively, demonstrating [73, 74] cell-type specificity for the Gαs variant in FD pathogenesis.