One such disorder is “neurodevelopmental disorder with hypotonia, neuropathy, and deafness” (MIM# 617519, abbreviated as “NEDHND”) and involves in deleterious variants of SPTBN4, named as beta spectrin non-erythrocytic 4. The gene discussed is SPTBN4; the disease is neurodevelopmental disorder with hypotonia, neuropathy, and deafness.