Biochemical analysis revealed that SCD patients showed higher levels of M1 phenotype markers, CCR7 and CD86, compared to healthy donors (HD) (p = 0,0029 and p = 0,045, respectively), with a large effect size for CCR7 (η2 = 0,9135) and a moderate but relevant effect size for CD86 (η2 = 0,6742). Here, CCR7 is linked to Schnyder corneal dystrophy.