Multiple studies have linked immune cell infiltration to lung cancer survival.29, 30, 31 This study revealed that ZBTB46 expression in LUAD and LUSC is significantly correlated with immune cell infiltration, including B-cells, CD8+ T-cells, CD4+ T-cells, macrophages, neutrophils, Dendritic Cells (DCs), NK cells, pDC, Th1 cells, Tem, TFH, NKT cells, Tem_CD8, and TReg. The gene discussed is ZBTB46; the disease is lung cancer.