In our exploration of LOY or LOX (Tables 3 and 4, Figures S7-S9, available at https://doi.org/10.1016/j.esmoop.2025.105539), we found that the combination of CHIP mutations with LOX had a 2.11-fold increased risk in CAD mortality (95% CI 1.20-3.71, P = 0.009). This evidence concerns the gene LOX and coronary artery disorder.