Risk factors of breast cancer patients for developing brain metastases include young age at diagnosis, multiple extracranial metastatic sites, high tumor grade, large tumor size, nodal involvement, multiple primary sites, and specific molecular subtypes such as human epidermal growth factor receptor 2 – positive (HER-2/neu+) and triple negative breast cancers (TNBC) [5]. Here, ERBB2 is linked to breast cancer.