TP53 and central nervous system cancer: In line with the study by Nakano et al. [18] who reported that low-grade gliomas (LGG) are associated with neurofibromatosis type 1 (NF1), SUFU PSVs were detected in patients with medulloblastoma and Gorlin syndrome, and that TP53 PSVs—in patients with medulloblastoma—our cohort showed similar associations between these phenotypes and these mutated genes (Table 6).