SEPTIN11 and frontotemporal dementia: Lastly, septin 11, a postsynaptic regulator of GABAergic synapse, highly expressed by PCs of the cerebellum, and localized to dendritic spines, and involved in dendritic arborization and maturation [114] has been associated with phagosome formation process [115] and discovered in sporadic frontotemporal lobar degeneration [116].