CD4 and metastatic neoplasm: Results of nonparametric tests demonstrated that infiltration degrees of B cells naïve, T cells CD4 naïve, T cells CD4 memory resting, T cells follicular helper, NK cells activated, dendritic cells resting and mast cells resting were lower in bone metastatic tumour samples than in primary tumour samples, while infiltrates of macrophages M0, NK cells resting and neutrophils were relatively higher in bone metastatic tumour samples (***p < 0.001, ** p < 0.01, *p < 0.05) (Figure S10C).