There have been reports of high expression of MGST1 in pancreatic cancer (Kuang et al., 2021), glioma (Yang et al., 2021), and melanoma (Zeng et al., 2020b; Zhang et al., 2023), and correlates with poor prognosis in multiple cancers, underscoring its broad relevance (Morgenstern et al., 2011). This evidence concerns the gene MGST1 and central nervous system cancer.