There have been reports of high expression of MGST1 in pancreatic cancer (Kuang et al., 2021), glioma (Yang et al., 2021), and melanoma (Zeng et al., 2020b; Zhang et al., 2023), and correlates with poor prognosis in multiple cancers, underscoring its broad relevance (Morgenstern et al., 2011). Here, MGST1 is linked to familial pancreatic carcinoma.