According to the results of univariate regression analysis and clinical experience, waist circumference, hypertension, diabetes, hyperlipidemia, BMI, WHR, HOMA-IR,VFA, use of intrauterine device, oestrogen receptor, progesterone receptor, HER2, E2, and LH were included in the multivariate regression model. The gene discussed is PLOD1; the disease is hypertensive disorder.