LncRNA-driven PCD networks in Parkinson’s disease demonstrate complementary control: Downregulated SNHG1 activates autophagy via miR-221/222-p27-mTOR signaling (Qian et al., 2019), while BDNF-AS upregulation promotes autophagic apoptosis through miR-125b-5p suppression (Fan et al., 2020), concurrent with NEAT1 stabilizing PINK1 to reinforce autophagic clearance (Yan et al., 2018). This evidence concerns the gene SNHG1 and Parkinson disease.