CDC histologically may resemble unclassified renal cell carcinoma (RCC) with medullary phenotype and SMARCB1 deficiency but differs by presenting a tubular or tubulopapillary pattern, whereas RMC exhibits a reticular pattern (28), regarding age range, CDC generally affects individuals over 55 years old, whereas RMC rarely occurs in patients over 40 years old (29), finally, from an immunohistochemical standpoint, the loss of INI1 expression in RMC is highlighted, which is an important method for distinguishing these neoplasms (30). Here, SMARCB1 is linked to hereditary clear cell renal cell carcinoma.