Conditional Wnt5a GOF, viral Wnt5a overexpression (Hosseini-Farahabadi et al. 2017), viral missense variant-containing Wnt5a overexpression (Hosseini-Farahabadi et al. 2017), and global Wnt5a knockout (Yamaguchi et al. 1999) cause micrognathia, but conditional Wnt5a LOF does not. The gene discussed is WNT5A; the disease is Micrognathia.