Craniofacial anomalies noted in patients with Robinow Syndrome that were identified in this study included midface hypoplasia and a trend toward hypertelorism only in the Wnt5a LOF group, while macrocephaly, shortened hard palate, and micrognathia were noted only in the Wnt5a GOF group (key findings are summarized in Appendix Table 6). Here, WNT5A is linked to Robinow syndrome.