In particular, Hexokinase-A (Hex-A), Phosphoglucose isomerase (Pgi), Phosphofructokinase (Pfk), Triose phosphate isomerase (Tpi), Glyceraldehyde-3-phosphate dehydrogenase 1 (Gapdh1), Enolase (Eno) and Pyruvate kinase (Pyk) were upregulated more than 2-fold in cyst cells relative to CySCs (Sainz de la Maza et al., 2022). Here, TPI1 is linked to cyst.