CD4 and neoplasm: Among the 247 clones composed of ≥80% of a single cell type (≥3 cells per clone) detected in lung tumors, defined here as cell type-specific clones, 20.6% were dominated by tumor cells, 11.3% by CD8+ T cells, 5.7% by regulatory CD4+ T cells (Treg), 47.8% by other CD4+ T cells, and 5.3% by B/plasma cells.